EAGLE Consortium

The EArly Genetics and Lifecourse Epidemiology (EAGLE) Consortium is a consortium of pregnancy and birth cohorts that aims to collaborate to investigate the genetic basis of phenotypes in antenatal and early life and childhood.

EAGLE covers a broad range of pathways and phenotypes, and will integrate closely with the DOHaD (developmental origins of health and disease) community.

All participating cohorts (1958 British Birth Cohort; ALSPAC; CHOP; COPSAC; DBC; Exeter Family Study; Generation R; HBCS; LISA+; MoBa; NTR; NFBC 66; Project Viva; Raine) have GWAS data available by July 1st 2009.

EAGLE working groups and leaders are listed below:

• Antenatal Growth (Vincent Jaddoe and Craig Pennell)
• Asthma, Allergy and Atopy (Hans Bisgaard, Klaus Bonnelykke and Joachim Heinrich)
• Behaviour and Cognition (Camilla Stoltenberg and Henning Tiemeier)
• Birth Biometry (Inga Prokopenko and Mark McCarthy)
• Blood Pressure (Becky Webster)
• Bone Health (Fernando Rivadeneira and Nic Timpson)
• Cardiovascular Risk Factors (Lyle Palmer and Vincent Jaddoe)
• Insulin and Metabolic Syndrome (Inga Prokopenko, Mark McCarthy and Tim Frayling)
• Postnatal Growth (Mark McCarthy, Tim Frayling and Marjo Ritta Jarvelin)
• Puberty (Elisabeth Widen and Marjo Ritta Jarvelin)